Custom Peptides
Cayman Chemical PalmItoylLcarnItInchLRI 10mg
A long-chain acylcarnitine; delivers palmitate into the mitochondria for fatty acid oxidation and energy production; inhibits lecithin:cholesterol acyltransferase activity in isolated rat plasma at 500 µM; serum and hepatic levels are increased in mice during cold exposure; protects against age-induced cold sensitivity in mice
Cayman Chemical 4-palmItamIdo TEMPO 10mg
A lipid-soluble spin label; incorporates into vesicles and cell membranes; has been used to study the entrapment of molecules within phosphatidylcholine vesicles
Cayman Chemical Sartrypyron B 10mg
A fungal metabolite; inhibits the growth of MCF-7, H460, and A375 cancer cells (GI50s = 17.8, 20.5, and 25 µM, respectively)
Cayman Chemical Acontum carmchal Dlsoln 10mg
A diterpene alkaloid with diverse biological activities; inhibits binding of α-bungarotoxin to rat neuronal α7 nAChRs (IC50 = 19 µM); repellent against adult red flour beetles in a filter paper assay at 3 mg/ml; lowers systolic blood pressure in a rat model of left renal artery ligation-induced hypertension at 75 mg/kg
Cayman Chemical L-ThyroxIn-N-methylamIde 10mg
A potential impurity found in commercial preparations of L-thyroxine
Cayman Chemical CurcumaZerumbon 10mg
A natural monocyclic sesquiterpene that potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM); inhibits SHH signaling and induces apoptosis in cancer cell lines
Cayman Chemical D-GlucosamIn-6-sulfate 10mg
A glycosaminoglycan; activates the glmS ribozyme from B. subtilis (200 µM); has been used to form polyvalent dendrimer conjugates that inhibit angiogenesis, cell proliferation, and scar tissue formation
Cayman Chemical PunIca grnatum PunIcaln 10mg
An ellagitannin with diverse biological activities; inhibits the SARS-CoV-2 spike RBD and ACE2 interaction (IC50 = 0.14 mg/ml); an inhibitor of carbonic anhydrase (IC50 = 1 µM); scavenges DPPH radicals and superoxide anions, as well as inhibits lipid peroxidation, in cell-free assays in a concentration-dependent manner; increases SOD and GPX activities, and decreases MDA levels, in the intestine in a mouse model of oxidative stress at 10 mg/kg per day
Cayman Chemical JWH 122 7mthylnaphthyl 10mg
Differs from JWH 122 in that the methyl group is attached to the naphthyl rings at the 7, rather than the 4, position
Cayman Chemical EltoprazInhydrochlorIde 10mg
A partial agonist at 5-HT1A, 5-HT1B, and 5-HT2B receptors (Kis = 40, 52, and 81 nM, respectively); decreases aggressive behavior in resident-intruder tests with rats (ID50 = 0.24 mg/kg)
Cayman Chemical DesoxImetason 10mg
A glucocorticoid; reverses TPA-induced increases in epidermal cell proliferation in SENCAR mice (0.001-0.1 mg topically); reduces TPA-induced expression of IL-6, COX-2, iNOS, and c-Jun mRNA levels in the skin of SENCAR mice
Cayman Chemical 1Stearoyl2Oleoylsnglycer 10mg
A phospholipid; has been used in the generation of LNPs for in vitro delivery of mRNA or nuclear-targeted plasmid DNA